BDBM50574093 CHEMBL4852822

SMILES COc1cccc(OC)c1-c1ccc(s1)-c1cnc2cc(ccn12)-c1cnn(C)c1

InChI Key InChIKey=KLSHWIBNWRYPMS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50574093   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574093(CHEMBL4852822)
Affinity DataIC50: 310nMAssay Description:Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574093(CHEMBL4852822)
Affinity DataIC50: 970nMAssay Description:Inhibition of Aurora A (unknown origin) using 5' FAM-LRRASLG-CONH2 peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574093(CHEMBL4852822)
Affinity DataIC50: 2.84E+3nMAssay Description:Inhibition of CSF-1R (unknown origin) using 5' FAM-KKKKEEIYFFF-CONH2 peptide as a substrate in the presence of ATP incubated for 60 mins by microflui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574093(CHEMBL4852822)
Affinity DataIC50: 5.43E+3nMAssay Description:Inhibition of RET (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574093(CHEMBL4852822)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NIK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574093(CHEMBL4852822)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NEK2 (unknown origin) using 5' FAM-KKLNRTLSVA-COOH peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574093(CHEMBL4852822)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed