BDBM50574109 CHEMBL4869856

SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2ncc(-c3ccc(s3)-c3ccc(F)cc3)n2c1

InChI Key InChIKey=CPZDGQKMNVXXNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50574109   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574109(CHEMBL4869856)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574109(CHEMBL4869856)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NEK2 (unknown origin) using 5' FAM-KKLNRTLSVA-COOH peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed