BDBM50574116 CHEMBL1453519

SMILES FC(F)(F)c1cc(nc(NCCc2ccccc2)n1)-c1ccco1

InChI Key InChIKey=RKVNKRKTJZOCBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50574116   

TargetToll-like receptor 8(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50574116(CHEMBL1453519)
Affinity DataIC50: 1.00E+5nMAssay Description:Negative modulator activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as inhibition of TL8-506 stimulated NF-kappaB activation preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed