BDBM50574120 CHEMBL4849835

SMILES OCc1ccc(CNc2nc(cc(n2)C(F)(F)F)-c2ccco2)cc1

InChI Key InChIKey=KJSRQLXFWCFXCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50574120   

TargetToll-like receptor 8(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50574120(CHEMBL4849835)
Affinity DataIC50: 6.20E+3nMAssay Description:Negative modulator activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as inhibition of TL8-506 stimulated NF-kappaB activation preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed