BDBM50574137 CHEMBL4861774

SMILES [H][C@@]12CCC(C(C)(O)CCCCCCOCCOCc3cn(CCOCCOCCOCCS(=O)(=O)c4ccc(C(=O)Nc5ccc(Cl)c(c5)-c5ccccn5)c(Cl)c4)nn3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C

InChI Key InChIKey=DZFZBMZVMBCIHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50574137   

TargetSmoothened homolog(Mouse)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50574137(CHEMBL4861774)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed