BDBM50574359 CHEMBL4856052

SMILES CN(C)CCNc1ccc2cc(ncc2c1)C(=O)Nc1cc(ccc1N)-c1cccs1

InChI Key InChIKey=KDTPUATYLVOWAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50574359   

TargetHistone deacetylase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574359(CHEMBL4856052)
Affinity DataIC50: 5nMAssay Description:Inhibition of human HDAC2 preincubated for 10 mins followed by tripeptide substrate addition and measured after 60 mins by fluorescence microplate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574359(CHEMBL4856052)
Affinity DataIC50: 0nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 10 mins followed by tripeptide substrate addition and measured after 60 mins by fluorescence mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed