BDBM50574361 CHEMBL4856764

SMILES Nc1ccc(cc1NC(=O)c1ccc2N(CCCN3CCOCC3)C(=O)Cc2c1)-c1cccs1

InChI Key InChIKey=MMXQZUUCRKYESL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50574361   

TargetHistone deacetylase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574361(CHEMBL4856764)
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 10 mins followed by tripeptide substrate addition and measured after 60 mins by fluorescence mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574361(CHEMBL4856764)
Affinity DataIC50: 5nMAssay Description:Inhibition of human HDAC2 preincubated for 10 mins followed by tripeptide substrate addition and measured after 60 mins by fluorescence microplate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed