BDBM50574366 CHEMBL4853087

SMILES Oc1c(cnn1-c1ccc(cn1)-c1nccs1)-c1ccc(cc1)C#N

InChI Key InChIKey=CMRFDYHBYZRUDW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50574366   

TargetProlyl hydroxylase EGLN2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574366(CHEMBL4853087)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant full length human N-terminal FLAG-tagged PHD1 expressed in baculovirus expression system using HIF1/C35 complex as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574366(CHEMBL4853087)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human N-terminal His-tagged/TEV cleavage fused PHD2 expressed in baculovirus infected insect cells using HIF1/C35 complex a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574366(CHEMBL4853087)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant full length human N-terminal 6His-tagged PHD3 expressed Escherichia coli using HIF1/C35 complex as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed