BDBM50574368 CHEMBL4858351

SMILES CCC(=O)Nc1ccc(nc1)-n1ncc(c1O)-c1ccc(cc1)C#N

InChI Key InChIKey=PMYJNKKMLWTZIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50574368   

TargetProlyl hydroxylase EGLN2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574368(CHEMBL4858351)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant full length human N-terminal FLAG-tagged PHD1 expressed in baculovirus expression system using HIF1/C35 complex as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574368(CHEMBL4858351)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human N-terminal His-tagged/TEV cleavage fused PHD2 expressed in baculovirus infected insect cells using HIF1/C35 complex a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574368(CHEMBL4858351)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant full length human N-terminal 6His-tagged PHD3 expressed Escherichia coli using HIF1/C35 complex as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed