BDBM50574401 CHEMBL4855559

SMILES CN(Cc1cccc(O)c1Cl)CC1(CCCC1)c1ccccc1F

InChI Key InChIKey=ZKLONXSLTZQICC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50574401   

TargetEstrogen receptor(Human)
X-Chem

Curated by ChEMBL
LigandPNGBDBM50574401(CHEMBL4855559)
Affinity DataIC50: 7.20nMAssay Description:Binding affinity to ERalpha D538G mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
X-Chem

Curated by ChEMBL
LigandPNGBDBM50574401(CHEMBL4855559)
Affinity DataIC50: 8.10nMAssay Description:Binding affinity to ERalpha Y537S mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
X-Chem

Curated by ChEMBL
LigandPNGBDBM50574401(CHEMBL4855559)
Affinity DataIC50: 15nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
X-Chem

Curated by ChEMBL
LigandPNGBDBM50574401(CHEMBL4855559)
Affinity DataIC50: 21nMAssay Description:Binding affinity to ERalpha S463P mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed