BDBM50574435 CHEMBL4862261

SMILES COc1ccc2c(O)c(ccc2c1)C(=O)Nc1ccc(CN)cc1

InChI Key InChIKey=TUCBVMZLIZJSTJ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50574435   

TargetKallikrein-6(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574435(CHEMBL4862261)
Affinity DataIC50: 7.18E+3nMAssay Description:Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPlasminogen(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574435(CHEMBL4862261)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of plasmin (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574435(CHEMBL4862261)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of KLK1 (unknown origin) assessed as release of AMC fluorescent product using H-PFR-AMC as substrate incubated for 30 mins by microplate r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKallikrein-6(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574435(CHEMBL4862261)
Affinity DataKi:  1.00E+3nMAssay Description:Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed