BDBM50575008 CHEMBL4851626

SMILES O=C(N1CCOCC1)c1ccc(Nc2nc(NCc3ccccc3)c3ccccc3n2)cc1

InChI Key InChIKey=XQBLEZWKILFATD-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50575008   

TargetCruzipain(Trypanosoma cruzi)
Federal University of Minas Gerais (Ufmg)

Curated by ChEMBL
LigandPNGBDBM50575008(CHEMBL4851626)
Affinity DataKi:  3.20E+3nMAssay Description:Competitive inhibition of Trypanosoma cruzi cruzain assessed as inhibition constant using varying levels of Z-FR-AMC as substrate by Michaelis-Menten...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Federal University of Minas Gerais (Ufmg)

Curated by ChEMBL
LigandPNGBDBM50575008(CHEMBL4851626)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Minas Gerais (Ufmg)

Curated by ChEMBL
LigandPNGBDBM50575008(CHEMBL4851626)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesiense MVAT4 rhodesain expressed in Pichia pastoris using Z-FR-AMC as substrate by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed