BDBM50575341 CHEMBL4856540

SMILES NS(=O)(=O)N1CCC2(CC1)C(c1cccc(c1)-c1cccc(c1)C(F)(F)F)C2(F)F

InChI Key InChIKey=LKYSXKWSOTUOKJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50575341   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50575341(CHEMBL4856540)
Affinity DataEC50:  430nMAssay Description:Positive allosteric modulation of human nAChRalpha7 expressed in HEK cells co-expressing RIC3 assessed as effect on acetylcholine-evoked current by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed