BDBM50575458 CHEMBL4871312

SMILES Nc1ccc(Cl)cc1-c1nnc[nH]1

InChI Key InChIKey=YLZNCOGLABONRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575458   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Sib Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50575458(CHEMBL4871312)
Affinity DataIC50: 34nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 7 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Sib Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50575458(CHEMBL4871312)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed