BDBM50575518 CHEMBL4860729

SMILES CCOc1nc2ccc(OC)cc2n1CCNC(=O)C1CCC1

InChI Key InChIKey=QIOYUWITBFJOES-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50575518   

TargetMelatonin receptor type 1B(Human)
Ach�

Curated by ChEMBL
LigandPNGBDBM50575518(CHEMBL4860729)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Ach�

Curated by ChEMBL
LigandPNGBDBM50575518(CHEMBL4860729)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in cAMP levels incubated at 28 degreeC by cellular dielectric spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Ach�

Curated by ChEMBL
LigandPNGBDBM50575518(CHEMBL4860729)
Affinity DataKi:  3.60nMAssay Description:Displacement of 2-[1251]-iodomelatonin from human MT1 receptor expressed in CHO cells incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Ach�

Curated by ChEMBL
LigandPNGBDBM50575518(CHEMBL4860729)
Affinity DataKi:  23nMAssay Description:Displacement of 2-[1251]-iodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed