BDBM50575875 CHEMBL4849776

SMILES OC(=O)CCc1cc(-c2cc(Cl)cc(Cl)c2)n(n1)-c1ccc(F)cc1

InChI Key InChIKey=VPQCQKZAXMGYJZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50575875   

TargetRetinoic acid receptor RXR-alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575875(CHEMBL4849776)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human RXRalpha transfected in human HEK293T cells co-expressing pFR/pRL-Luc incubated for 14 to 16 hrs by hybrid reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575875(CHEMBL4849776)
Affinity DataEC50:  470nMAssay Description:Agonist activity at human RXRbeta transfected in human HEK293T cells co-expressing pFR/pRL-Luc incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575875(CHEMBL4849776)
Affinity DataEC50:  1.64E+3nMAssay Description:Agonist activity at human RXRgamma transfected in human HEK293T cells co-expressing pFR/pRL-Luc incubated for 14 to 16 hrs by hybrid reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed