BDBM50576134 CHEMBL4851995

SMILES Fc1cc(ccc1CO[C@H]1C[C@H](C1)N=C=S)-c1ccc(OC(F)(F)F)c(F)c1

InChI Key InChIKey=ROKVPWHHBYTRKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576134   

TargetCathepsin K(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50576134(CHEMBL4851995)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human Cathepsin K using Z-Phe-Arg-AMC as fluorogenic substrate preincubated for 120 mins followed by substrate addition by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50576134(CHEMBL4851995)
Affinity DataIC50: 97nMAssay Description:Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed