BDBM50576275 CHEMBL4873599

SMILES C[C@@H](c1nn(CCO)c2c1nc(C)[nH]c2=O)c1ccc(c(F)c1)C(F)(F)F

InChI Key InChIKey=WBHATACQVADBBY-UHFFFAOYSA-N

Data  1 KI  7 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50576275   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Merck

Curated by ChEMBL

LigandBDBM50576275(CHEMBL4873599)Copy SMILESCopy InChI

Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human PDE4More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
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TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Merck

Curated by ChEMBL

LigandBDBM50576275(CHEMBL4873599)Copy SMILESCopy InChI

Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human PDE5More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
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TargetO43924/P16499/P18545/P35913/P51160/Q13956(Human)
Merck

Curated by ChEMBL

LigandBDBM50576275(CHEMBL4873599)Copy SMILESCopy InChI

Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human PDE6More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Merck

Curated by ChEMBL

LigandBDBM50576275(CHEMBL4873599)Copy SMILESCopy InChI

Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human PDE7More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Merck

Curated by ChEMBL

LigandBDBM50576275(CHEMBL4873599)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PDE9More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck

Curated by ChEMBL

LigandBDBM50576275(CHEMBL4873599)Copy SMILESCopy InChI

Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human PDE10More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Merck

Curated by ChEMBL

LigandBDBM50576275(CHEMBL4873599)Copy SMILESCopy InChI

Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human PDE11More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck

Curated by ChEMBL

LigandBDBM50576275(CHEMBL4873599)Copy SMILESCopy InChI

Affinity DataKi:  1.10nMAssay Description:Inhibition of human PDE2More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL