BDBM50576518 CHEMBL4848638

SMILES [#6]\[#6](-[#6]-[#6]\[#6]=[#6](\[#6]-[#8])-[#6]-[#8])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6][C@]1([#6])[#6]-[#6]-c2c(-[#8]1)c(-[#6])cc1oc(=O)c(cc21)-[#6](-[#6])=O

InChI Key InChIKey=JLNAQSXKMMQKIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576518   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50576518(CHEMBL4848638)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli BL21 (DE3) cells preincubated for 10 mins followed by arachidonic acid addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50576518(CHEMBL4848638)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-LOX product formation preincubated for 10 mins before addition of AA and A23187 and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed