BDBM50576541 CHEMBL4869193

SMILES [O-][S+]1CCc2c(C1)c(nc1ccc3[nH]ncc3c21)-c1c[nH]nc1C(F)(F)F

InChI Key InChIKey=UGLMDRPTTBWXIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576541   

TargetCyclin-A1/Cyclin-dependent kinase 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576541(CHEMBL4869193)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576541(CHEMBL4869193)
Affinity DataIC50: 17nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed