BDBM50576556 CHEMBL4856733

SMILES Fc1cc2[nH]ncc2c2c3CCCCc3c(nc12)-c1c[nH]nc1C(F)(F)F

InChI Key InChIKey=QZEZKSMIUTYGRU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50576556   

TargetCyclin-A1/Cyclin-dependent kinase 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576556(CHEMBL4856733)
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576556(CHEMBL4856733)
Affinity DataIC50: 12nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576556(CHEMBL4856733)
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK1/cyclin B1 (unknown origin) in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576556(CHEMBL4856733)
Affinity DataIC50: 33nMAssay Description:Inhibition of CDK2/cyclin E1 (unknown origin) in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576556(CHEMBL4856733)
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin) in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576556(CHEMBL4856733)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin) in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576556(CHEMBL4856733)
Affinity DataIC50: 538nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576556(CHEMBL4856733)
Affinity DataIC50: 31nMAssay Description:Inhibition of wild type FLT3 (unknown origin) using AGLT peptide substrate in presence of [32P]gammaATP by image analyserMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed