BDBM50576703 CHEMBL4866650

SMILES COc1cc(CC(=O)NCCOCCOCCNC(=O)c2cccc(c2)-c2cccnc2)cc(OC)c1OC

InChI Key InChIKey=LJEDDEDJFDYMNZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576703   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576703(CHEMBL4866650)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of human recombinant SIRT2 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
The University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576703(CHEMBL4866650)
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of human recombinant SIRT2 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed