BDBM50576807 CHEMBL4876793

SMILES CNC(=O)c1cc2C[C@@]3(Cc2cc1F)N(C(C)C)C(=S)N(C3=O)c1cnc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=VUBVBCFCFVJNCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576807   

TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50576807(CHEMBL4876793)
Affinity DataIC50: 112nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50576807(CHEMBL4876793)
Affinity DataIC50: 178nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed