BDBM50577138 CHEMBL4847749

SMILES COC(=O)c1c(C)cc(O)c(C\C=C(/C)CCCC2=C\C(OC2=O)=C/C(C)(C)O)c1O

InChI Key InChIKey=LGMYKTHBAQWEFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577138   

TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577138(CHEMBL4847749)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577138(CHEMBL4847749)
Affinity DataIC50: 4.07E+4nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed