BDBM50577139 CHEMBL4846858

SMILES C\C(CCCC1=C\C(OC1=O)=C/C(C)(C)O)=C/Cc1c(O)cc(C)c(C(O)=O)c1O

InChI Key InChIKey=VFPRFCPQXQJWDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577139   

TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577139(CHEMBL4846858)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577139(CHEMBL4846858)
Affinity DataIC50: 5.14E+4nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed