BDBM50577413 CHEMBL4874944

SMILES C\C(=C/c1ccc2O[C@@H](CCC(O)=O)CN(c2c1)S(=O)(=O)c1ccc(F)c(c1)C(F)(F)F)c1c(F)cccc1Cl

InChI Key InChIKey=VIQZVODLWNDRBM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50577413   

TargetNuclear receptor ROR-gamma(Human)
Lycera

Curated by ChEMBL
LigandPNGBDBM50577413(CHEMBL4874944)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human His-tagged RORgamma-LBD expressed in Sf9 cells assessed as inhibition of N-terminal biotinylated co-activator SRC1 recruitm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Lycera

Curated by ChEMBL
LigandPNGBDBM50577413(CHEMBL4874944)
Affinity DataEC50:  411nMAssay Description:Agonist activity at human ROR-gamma LBD expressed in HEK293 cells assessed as transcriptional activity in presence of ursolic acid by Gal4-luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50577413(CHEMBL4874944)
Affinity DataEC50:  6.00E+3nMAssay Description:Agonist activity at human PXR-gamma expressed in HEK293 cells assessed as transcriptional activity in presence of ursolic acid by Gal4-luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed