BDBM50577752 CHEMBL4875108

SMILES CCCCc1nc(=O)c(C(=O)N2CCC(C2)c2ccncc2)c(O)n1-c1c(OC)cccc1OC

InChI Key InChIKey=UYALXHDMGGCLAX-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50577752   

TargetApelin receptor(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50577752(CHEMBL4875108)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293T cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetApelin receptor(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50577752(CHEMBL4875108)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293T cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetApelin receptor(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50577752(CHEMBL4875108)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at rat APJ receptor expressed in HEK293T cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetApelin receptor(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50577752(CHEMBL4875108)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at rat APJ receptor expressed in HEK293T cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed