BDBM50577757 CHEMBL4874296

SMILES CC1(C)N(Cc2ccccc2)Cc2c(NC(=O)c3ccccc3)n[nH]c12

InChI Key InChIKey=UCEJVJFDKNVXDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577757   

TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577757(CHEMBL4874296)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of N-terminal GST-tagged human TRKA (436 to 790 residues) expressed in baculovirus infected Sf21 cells using TK as substrate in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577757(CHEMBL4874296)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of human intracellular domain of TRKA expressed in Sf9 cells incubated for 1 hr by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed