BDBM50578014 CHEMBL4872952

SMILES Cc1n[nH]c2ccc(cc12)-c1cncc(N[C@@H](CO)c2cccc(F)c2)n1

InChI Key InChIKey=VKXBNFWRQLNUFV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50578014   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50578014(CHEMBL4872952)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) incubated for 2 hrs in presence of ATP by FRET based LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50578014(CHEMBL4872952)
Affinity DataIC50: 34nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50578014(CHEMBL4872952)
Affinity DataIC50: 496nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50578014(CHEMBL4872952)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50578014(CHEMBL4872952)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed