BDBM50578759 CHEMBL4860491

SMILES COc1ccc(cc1-c1cnc(nc1CN1[C@@H](C)[C@H](OC1=O)c1ccnc(c1)C(F)(F)F)N(C)C)-c1ccc(cc1C)C(O)=O

InChI Key InChIKey=HJOMKCKCPKGETQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50578759   

TargetCholesteryl ester transfer protein(Human)
Merck

Curated by ChEMBL

LigandBDBM50578759(CHEMBL4860491)Copy SMILESCopy InChI

Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/24/2022
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50578759(CHEMBL4860491)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [S35]-MK-0499 binding to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/24/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL