BDBM50579208 CHEMBL4867107

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)c(C)cn(-c2c(Cl)cccc2Cl)c3=O)cc1

InChI Key InChIKey=FSRYXGSLNYBDRQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50579208   

TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50579208(CHEMBL4867107)
Affinity DataIC50: 2nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50579208(CHEMBL4867107)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed