BDBM50579480 CHEMBL4877440

SMILES COc1ccc(NC(=O)Nc2ccc(Oc3ncnc4cc(ccc34)N(C)C)cc2)cc1

InChI Key InChIKey=RTWJZWFAMFOLDK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50579480   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50579480(CHEMBL4877440)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50579480(CHEMBL4877440)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant full length GST-AURKB using tetra(-LRRASLG) peptide as substrate incubated for 20 mins by ATP Kinase Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50579480(CHEMBL4877440)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant GST-AURKA (residues Ser123 to Ser401) (unknown origin) expressed in Sf9 insect cells using tetra(-LRRASLG) peptide as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed