BDBM50580180 CHEMBL5073653

SMILES CC(C)Oc1nc(cc2ccccc12)-c1n[nH]c(=O)[nH]1

InChI Key InChIKey=SMMHPCZFSDSGPW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580180   

TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50580180(CHEMBL5073653)
Affinity DataIC50: 10nMAssay Description:Inhibition of Btk (unknown origin) assessed as inhibition of phosphorylation of FAM-labelled peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50580180(CHEMBL5073653)
Affinity DataEC50:  100nMAssay Description:Inhibition of human Btk in human Raji cells assessed as PhosY223 measured after 30 mins by cellular HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed