BDBM50580310 CHEMBL5088875

SMILES Nc1cc(F)ccc1NC(=O)c1ccc(CCNc2nc(N)n3nc(nc3n2)-c2ccco2)cc1

InChI Key InChIKey=OJSWNBSTDSTLPO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50580310   

TargetAdenosine receptor A2a(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50580310(CHEMBL5088875)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]SCH58261 from adenosine A2A receptor membrane (unknown origin) measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50580310(CHEMBL5088875)
Affinity DataIC50: 174nMAssay Description:Inhibition of HDAC1 (unknown origin) assessed as release of 7-amino-4-methylcoumarin incubated in room temperature for 15 min measured by Spectra max...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50580310(CHEMBL5088875)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) assessed as release of 7-amino-4-methylcoumarin incubated in room temperature for 15 min measured by Spectra max...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed