BDBM50580470 CHEMBL5075883

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(C)(C)F)c1c(F)cc(cc1F)N1CC(C1)N(C)C

InChI Key InChIKey=WJDAHKFBNSZJKZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580470   

TargetEstrogen receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50580470(CHEMBL5075883)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of Fluormone ES2 from full length human ERalpha incubated for 60 min by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50580470(CHEMBL5075883)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells incubated for 4 hrs in presence of anti-ERalpha rabbit monoclonal antibodies measured after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed