BDBM50580491 CHEMBL5088627

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(C)(C)F)c1c(F)cc(cc1F)-c1ccc(cc1)C(N)=O

InChI Key InChIKey=KBAAFZCYQAWBJE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580491   

TargetEstrogen receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50580491(CHEMBL5088627)
Affinity DataIC50: 22nMAssay Description:Displacement of Fluormone ES2 from full length human ERalpha incubated for 60 min by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50580491(CHEMBL5088627)
Affinity DataEC50:  0.660nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells incubated for 4 hrs in presence of anti-ERalpha rabbit monoclonal antibodies measured after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed