BDBM50580607 CHEMBL5070239

SMILES Nc1ncnc2n(CCCCCN3CCN(CC3)C(=O)\C=C\C(F)(F)F)nc(-c3cc(F)cc(c3)C(F)(F)F)c12

InChI Key InChIKey=FAJMNJHLDPNTLS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50580607   

TargetFibroblast growth factor receptor 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580607(CHEMBL5070239)
Affinity DataIC50: 65nMAssay Description:Inhibition of human FGFR2 (458 to 768 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580607(CHEMBL5070239)
Affinity DataIC50: 97nMAssay Description:Inhibition of human FGFR3 (450 to 758 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580607(CHEMBL5070239)
Affinity DataIC50: 101nMAssay Description:Inhibition of human FGFR1 (459 to 765 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580607(CHEMBL5070239)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human FGFR4 (445 to 753 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed