BDBM50580627 CHEMBL5083953

SMILES Cc1ccc(S(=O)(=O)n2cc(C(=O)C(=O)N[C@H](C(=O)NCC(=O)O)c3c[nH]c4ccccc34)c3ccccc32)cc1

InChI Key InChIKey=UTQPBHDQTRKBIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580627   

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580627BDBM50580627(CHEMBL5083953)
Affinity DataIC50: 540nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580627BDBM50580627(CHEMBL5083953)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed