BDBM50580641 CHEMBL5094401

SMILES [H][C@@]12CN(C[C@]1([H])CN(C2)c1cc(ccc1F)C(O)=O)c1c(C)n[nH]c1C

InChI Key InChIKey=GDJKFOMCLVYRRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580641   

TargetTransthyretin(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50580641(CHEMBL5094401)
Affinity DataIC50: 2.82E+3nMAssay Description:Binding affinity to human plasma TTR tetramer assessed as displacement of diclofenac-coupled FITC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinol-binding protein 4(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50580641(CHEMBL5094401)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]-all trans retinol from human urine biotinylated RBP4 incubated for 16 hrs measured by Scintillation Proximity AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed