BDBM50580829 CHEMBL5080086

SMILES CCC(=O)N(CC1(COC1)N1CCN(Cc2ccccc2)CC1)c1ccccc1

InChI Key InChIKey=HCYGWCRNGVMSHQ-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50580829   

TargetMu-type opioid receptor(Human)
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50580829(CHEMBL5080086)
Affinity DataEC50:  253nMAssay Description:Agonist activity at human MOR expressed in CHO-K1 cells assessed as reduction in forskolin-induced cAMP production incubated for 45 mins by by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50580829(CHEMBL5080086)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of hERG expressed in CHO cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50580829(CHEMBL5080086)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma-1 receptor transfected in HEK293 membranes incubated for 120 mins measured by microBeta scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50580829(CHEMBL5080086)
Affinity DataKi:  107nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 60 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed