BDBM50581685 CHEMBL5074641

SMILES CCOc1nc(nc(=O)n1-c1ccccc1)N(C)C

InChI Key InChIKey=ZUKAYYQLPXUEKJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581685   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50581685(CHEMBL5074641)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli assessed as dissociation constant by SPR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50581685(CHEMBL5074641)
Affinity DataIC50: 3.07E+5nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed