BDBM50581709 CHEMBL5075691

SMILES Cc1cccc(c1)N2c3cc(ccc3C(=NC2=O)N(C)C)Cl

InChI Key InChIKey=CQCXBTFANPRPTE-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50581709   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50581709(CHEMBL5075691)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged MAT2A expressed in Escherichia coli using methionine and ATP as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)