BDBM50581806 CHEMBL5080867

SMILES [H][C@@]12COP(O)(=O)O[C@@]3([H])[C@@H](F)[C@@H](O[C@]3([H])CO[P@@](=O)(OCOC(=O)OC(C)C)O[C@@]1([H])[C@@H](F)[C@@H](O2)n1cnc2c(N)ncnc12)n1cnc2c(N)ncnc12

InChI Key InChIKey=GVIFYDSYPLNPOJ-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50581806   

TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581806(CHEMBL5080867)
Affinity DataEC50:  1.93E+3nMAssay Description:Activation of wild-type human STING expressed in HEK293T cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activation measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581806(CHEMBL5080867)
Affinity DataEC50:  320nMAssay Description:Activation of wild-type human STING expressed in HEK293T cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activation measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581806(CHEMBL5080867)
Affinity DataEC50:  1.71E+3nMAssay Description:Activation of wild-type human STING expressed in digitonin treated human THP1-Dual cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581806(CHEMBL5080867)
Affinity DataEC50:  200nMAssay Description:Activation of wild-type human STING expressed in human THP1-Dual cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activation measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed