BDBM50581990 CHEMBL5075899

SMILES CCN1CCN(CC1)c1nc(N)nc2n(CCCN3CCCC3)cnc12

InChI Key InChIKey=VOZBGKKZIZMDOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581990   

TargetToll-like receptor 9(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50581990(CHEMBL5075899)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human TLR9 expressed in HEK-blue-HTLR7 cells assessed as inhibition of CpGB-induced NFkappaB activation measured after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50581990(CHEMBL5075899)
Affinity DataIC50: 4.94E+3nMAssay Description:Antagonist activity at human TLR7 expressed in HEK-blue-HTLR7 cells assessed as inhibition of CL264-induced NFkappaB activation measured after overni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed