BDBM50582097 CHEMBL5070941

SMILES ClCC(=O)N[C@@H](CC=C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccccc1

InChI Key InChIKey=DMHYAQLYAFULCU-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582097   

TargetProcathepsin L(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50582097(CHEMBL5070941)
Affinity DataIC50: 20nMAssay Description:Inhibition of Cathepsin L (unknown origin) using Z-Leu-Arg-AMC fluorometric dipeptide as substrate peincubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50582097(CHEMBL5070941)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of recombinant SARS-CoV-2 main protease using DABCYL-KTSAVLQSGFRKME-EDANS as fluorescent substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSpike glycoprotein(2019-nCoV)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50582097(CHEMBL5070941)
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized SARS-CoV-2 spike glycoprotein assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed