BDBM50582101 CHEMBL5073127

SMILES CCNc1cc(Oc2c(OC)cc3cc(ccc3c2OC)C#N)nc(Nc2ccc(cc2)C#N)n1

InChI Key InChIKey=KBPBNZRHOWWRCO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50582101   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582101(CHEMBL5073127)
Affinity DataIC50: 60nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582101(CHEMBL5073127)
Affinity DataIC50: 90nMAssay Description:Inhibition of HIV1 reverse transcriptase E138K mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582101(CHEMBL5073127)
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582101(CHEMBL5073127)
Affinity DataIC50: 160nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582101(CHEMBL5073127)
Affinity DataIC50: 430nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582101(CHEMBL5073127)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase F227L/V106A double mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582101(CHEMBL5073127)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582101(CHEMBL5073127)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed