BDBM50582135 CHEMBL5087446

SMILES Cc1ccc(C(=O)NCC(=O)Nc2ccc3NC(=O)\C(=C/c4cnc[nH]4)c3c2)c(=O)n1Cc1ccc(F)c(F)c1

InChI Key InChIKey=HJUAIOQSNLTXLS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582135   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
University of Pisa

Curated by ChEMBL

LigandBDBM50582135(CHEMBL5087446)Copy SMILESCopy InChI

Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
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TargetAurora kinase A(Human)
University of Pisa

Curated by ChEMBL

LigandBDBM50582135(CHEMBL5087446)Copy SMILESCopy InChI

Affinity DataIC50: 193nMAssay Description:Inhibition of recombinant full length human His-tagged AURA expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL