BDBM50582146 CHEMBL5085478

SMILES Oc1ccc(c(F)c1)-c1ccc2c(n[nH]c2c1)-c1ccc(cc1)N1CCNCC1

InChI Key InChIKey=QTPVWHQITHNCPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582146   

TargetFibroblast growth factor receptor 1(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50582146(CHEMBL5085478)
Affinity DataIC50: 204nMAssay Description:Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50582146(CHEMBL5085478)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of wild type FGFR2 (unknown origin) (461 to 763 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50582146(CHEMBL5085478)
Affinity DataIC50: 9.15E+5nMAssay Description:Inhibition of wild type FGFR3 (unknown origin) using Tyr04 peptide as substrate incubated for 1 hr by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed