BDBM50582346 CHEMBL5079785

SMILES CS(=O)(=O)c1ccc(cc1)-n1ccc2cnc(Nc3cnn(CCCCCCC(=O)NO)c3)nc12

InChI Key InChIKey=DQPZPLZQAITXBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582346   

TargetTyrosine-protein kinase JAK2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582346(CHEMBL5079785)
Affinity DataIC50: 16nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 60 mins followed by reagent A addition and measured after 60 mins in presence of ATP by using mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582346(CHEMBL5079785)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed