BDBM50582374 CHEMBL5077078

SMILES COc1cccc(Cn2ccc3cnc(Nc4cnn(CCCCCCC(=O)NO)c4)nc23)c1

InChI Key InChIKey=YZXHJTBXNJUQCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582374   

TargetTyrosine-protein kinase JAK2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582374(CHEMBL5077078)
Affinity DataIC50: 209nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 60 mins followed by reagent A addition and measured after 60 mins in presence of ATP by using mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582374(CHEMBL5077078)
Affinity DataIC50: 29nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed